Product Introduction:
Ketoconazole is an antifungal medication primarily used to treat fungal infections. It belongs to the class of medications known as azole antifungals.

Uses:

1. Fungal Infections: Ketoconazole is effective against a variety of fungal infections including:
   
   • Skin infections like athlete’s foot, jock itch, ringworm, and yeast infections.
   • Systemic infections such as blastomycosis, histoplasmosis, and coccidioidomycosis.
   • Fungal infections of the nails.

Benefits:

• Ketoconazole effectively targets fungal infections by inhibiting the synthesis of ergosterol, a crucial component of fungal cell membranes, thereby disrupting fungal growth and replication.
• It offers a broad spectrum of activity against various fungal pathogens.
• Ketoconazole is available in different formulations including creams, shampoos, and oral tablets, offering versatility in treatment options.

Side Effects:
While ketoconazole is generally well-tolerated, some common side effects may include:

• Nausea and vomiting
• Abdominal pain
• Headache
• Dizziness
• Skin irritation or rash (with topical formulations)
• Changes in taste sensation

In rare cases, severe side effects like liver problems or allergic reactions may occur. If you experience any unusual symptoms, seek medical attention promptly.

Safety Advice:

• Use ketoconazole as directed by your healthcare provider. Follow dosage instructions carefully.
• Inform your doctor about any pre-existing medical conditions, allergies, or medications you are taking, especially if you’re pregnant or breastfeeding.
• Topical ketoconazole formulations are for external use only. Avoid contact with eyes, nose, mouth, and other mucous membranes.
• If using ketoconazole shampoo, rinse thoroughly after application.
• Avoid alcohol consumption while taking oral ketoconazole, as it may increase the risk of liver damage.
• Report any unusual symptoms or side effects to your healthcare provider promptly.

Interaction with Drugs:

• Ketoconazole may interact with various medications, including:
  
  • Antacids, proton pump inhibitors, or H2-receptor antagonists, which may reduce the absorption of oral ketoconazole.
  • Certain medications metabolized by the liver enzymes CYP3A4 or CYP2C9, potentially leading to increased or decreased levels of these drugs.
  • Statins (cholesterol-lowering medications), which may increase the risk of muscle toxicity when used concomitantly with ketoconazole.
  • Warfarin and other anticoagulants, which may require dosage adjustments due to potential interactions with ketoconazole.

Always consult your healthcare provider or pharmacist about potential drug interactions before starting ketoconazole or any other medication.

More Information:
For additional information on ketoconazole, including dosage guidelines, precautions, and potential side effects, you can visit the MedlinePlus page on Ketoconazole.