Ofev
EQUIVALENT US BRAND NAME: Ofev
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We will deliver the Indian brand medicine based on availability.
Product Introduction: Nintedanib is a medication that belongs to a class of drugs known as tyrosine kinase inhibitors. It was initially developed by Boehringer Ingelheim and is sold under the brand name Ofev. It was approved by the U.S. Food and Drug Administration (FDA) in 2014 for the treatment of idiopathic pulmonary fibrosis (IPF), a progressive lung disease characterized by scarring of lung tissue.
Uses: Nintedanib is primarily used for the treatment of idiopathic pulmonary fibrosis (IPF), where it helps to slow down the progression of the disease and improve lung function. It works by targeting multiple tyrosine kinases, which are enzymes involved in various cellular processes, including the growth and development of fibrotic tissue in the lungs.
Benefits:
- Slows down the progression of idiopathic pulmonary fibrosis (IPF)
- Improves lung function and exercise tolerance
- Reduces the risk of acute exacerbations in IPF patients
Side Effects: Common side effects of nintedanib may include:
- Nausea and vomiting
- Diarrhea
- Abdominal pain
- Decreased appetite
- Liver enzyme elevation
- Headache
- Fatigue
Less common but more serious side effects may include:
- Bleeding problems
- Hypertension (high blood pressure)
- Liver toxicity
- Gastrointestinal perforation (rare)
Safety Advice:
- Take nintedanib exactly as prescribed by your healthcare provider.
- Do not crush, chew, or split the capsules; swallow them whole with water.
- Inform your doctor about all medications, supplements, and herbal products you are taking before starting nintedanib.
- Regularly monitor liver function tests and blood pressure while on nintedanib treatment.
- Report any signs of bleeding, gastrointestinal problems, or liver dysfunction to your doctor immediately.
- Avoid consuming grapefruit or grapefruit juice while taking nintedanib.
Interaction with Drugs: Nintedanib may interact with certain medications, including:
- Anticoagulants (blood thinners) such as warfarin: Nintedanib may increase the risk of bleeding when used concomitantly with anticoagulants.
- CYP3A4 inhibitors and inducers: Drugs that inhibit or induce the CYP3A4 enzyme may affect the metabolism of nintedanib, leading to altered blood levels and efficacy.
- Proton pump inhibitors (PPIs): Concurrent use of nintedanib with PPIs may increase the risk of gastrointestinal adverse effects.
More Information: For more information on nintedanib, including its uses, side effects, and safety precautions, you can visit the MedlinePlus page on nintedanib: Nintedanib – MedlinePlus
Note :
- Do not put the quantity above 30 days. (eg. if prescription is 2 pills per day then you can purchase one month of supply of 60 pills)
- We will deliver medicine of Indian brand within 30 days of supply.
- Prescription and ID are required to purchase each month of supply.
- If a doctor writes 30 days of medicines with 3 times refills then you can use the same prescription for 3 consecutive months for purchasing medicine using reorder option and uploading the same prescription and your ID 3 times.